Folate has been recommended to help in depression and may have a calming effect. There is a prescription form of Metafolin called Deplin which comes in 8 milligrams (or 8000 micrograms), but there is a disclaimer that Metafolin may aid in the growth of tumors/cancer, especially in the GI tract (which makes sense because Metafolin is used in DNA synthesis and rapidly dividing cells need to make DNA). Note it won't cause cancer, but it may aid in the growth/spread of a tumor if it is there. Also if you are going through cancer treatment, don't take folate supplements. Anyways, if you want to see if Metafolin may help your symptoms, this could be a good starting dose with less risk.
Posted by Health-Is-Wealth on December 21 2013 | Verified Purchase
Why Solgar feel it's necessary to include mannitol - seems odd, though I'm sure there's a valid reason (?). Even though the label states "provides a dietarily insignificant amount of sugar alcohol", my experience has proven that a manufacturer's "insignificant" is usually a customer's nightmare. Mannitol is listed first, indicating these tabs contain more of that than the other fillers. Even if you don't have a genetic reason for taking activated folate, it's probably more beneficial than the awful stuff used in cheap B complexes. Unfortunately the glucosamine salt Quatrefolic (e.g. Doctor's Best) is unsuitable allergy/asthma sufferers. I thought this would be the safer choice but it's also unsuitable. Suggest getting one with no mannitol or trying Quatrefolic if you know you tolerate glucosamine. Won't be purchasing this again - prefer California Xtracts Calcium Folinate. I've read that folinic acid is supposed to be OK regardless of genetic defects - will see how it goes. If this review was helpful to you, please click YES below - thank you. For reviews of all the products I have purchased from iHerb, please click my username above.
Posted by iHerb Customer on May 17 2016 | Verified Purchase
They now charge 50€ additional for self handling of customs! I will never order from Iherb again!!
Posted by iHerb Customer on August 24 2016 | Verified Purchase
This cause me to have blood stool. Bought this with the hope of curing my depression but I don't feel anything at all! May be this is not for me :(
Posted by iHerb Customer on January 30 2009 | Verified Purchase
No real results at this point....
Posted by iHerb Customer on March 27 2017 | Verified Purchase
I am really disappointing and frustrating because i haven't received the product yet. I have ordered it on 13 February. i would like to complain why it take so long time to deliver the product to me.
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