I take 90000 mg/daily, the recommended therapudic amount for arthritis. I've tried numerous other homeopathic remedies but Nopal Cactus is the only thing that has worked - and very quickly. I live in an upstairs apt. with a steep staircase. After only 4 weeks on Nopal Cactus, I can go up and down like a normal person instead of one step at a time. I just placed my 2nd order with iHerb.